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About Limbs. All items sold on this website are reproductions (replicas). All Bone Clones® products are made in the USA. No real or natural bone material is In some cases modification includes the fusion or loss of bones. The ancestral tetrapod pentadactyl limb plan consists of three parts: upper (arm or...implantation to treat human lower limb long bone nonunion. Materials and Methods: It is a prospective clinical trial for evaluating the safety of using autologus bone marrow derived mesenchymal stromal cells for treating nonunion. Orthopedic surgeons evaluated 12 patients with lower limb long bone nonunion for participation in this study.